Kinetic and thermodynamic evaluation of phosphate ions binding onto sevelamer hydrochloride
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چکیده
منابع مشابه
Kinetic and thermodynamic evaluation of phosphate ions binding onto sevelamer hydrochloride.
Sevelamer hydrochloride is the first non-aluminium, non-calcium-based phosphate binder developed for the management of hyperphosphatemia in end stage renal diseases. It is a synthetic ion-exchange polymer which binds and removes phosphate ions due to the high content of cationic charge associated with protonated amine groups on the polymer matrix. This is the first in-depth study investigating ...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutics
سال: 2014
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2014.08.004